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Cirrhosis is advanced scarring of the liver caused by many diseases and conditions, including hepatitis or alcohol use disorder Hepatic encephalopathy occurs in 30% to 40% of people who have cirrhosis. Each time the liver is injured — whether by alcohol use disorder or another cause, such as infection — it tries to repair itself

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In the process, scar tissue forms. Hepatic encephalopathy may be caused by injury to the liver, cancer or a chronic liver disease that results in liver failure, such as cirrhosis Cirrhosis happens because of liver injury, such as the damage caused by inflammation in mash

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As the liver tries to stop inflammation, it creates areas of scarring, also called fibrosis.

Because cirrhosis has a variety of causes and complications, there are many potential avenues of approach A combination of increased screening, lifestyle changes and new medicines may improve outcomes for people with liver damage, if started early. Several liver diseases — including hepatitis infection, alcoholic liver disease, fatty liver disease and a bile duct disorder called primary biliary cholangitis — can result in cirrhosis. Liver disease can be passed through families, called inherited

Anything that damages the liver also can cause liver problems, including viruses, alcohol use and obesity. Several types of cancer can form in the liver The most common type of liver cancer is hepatocellular carcinoma, which begins in the main type of liver cell (hepatocyte) Other types of liver cancer, such as intrahepatic cholangiocarcinoma and hepatoblastoma, are much less common.

Untreated autoimmune hepatitis can lead to scarring of the liver, called cirrhosis

It can also eventually lead to liver failure When diagnosed and treated early, however, autoimmune hepatitis often can be controlled with medicines that suppress the immune system. Having a larger than usual liver is a sign of a serious condition, such as liver disease, congestive heart failure or cancer. Ongoing inflammation in the liver can lead to bile duct inflammation and damage known as cholangitis

At times, this can lead to permanent scarring of liver tissue, called cirrhosis.